API Screening Scheme
Material properties
In the synthesis of raw materials and intermediates, the particle size of the material is different, and the fineness of the powder is not uniform, which is depreciated or even rejected. Because the content of plant fiber exceeds the standard, the value of medicinal powder cannot be improved. The particle size of the pills is different, the size of the pills is different, and the specifications of the raw materials are different. There are nearly a thousand kinds. Strict requirements, can not damage, damage, such as capsule pellets raw materials.
Production process
Raw material extraction - filtration - crystallization - separation - drying - sieving - inner packaging - outer packaging
Extraction of raw materials: According to the solubility of various components in Chinese herbal medicines in solvents, a solvent with high solubility for active components and low solubility for components that do not need to be dissolved is selected, and the method of dissolving the active components from the tissue of the medicinal material is called solvent extraction.
Filtration: Filtration refers to a unit operation of separating solid matter particles suspended in a gas or liquid, using a porous material (filter medium) to pass the gas or liquid in the suspension (filter slurry) (filtrate), intercepting The solid particles (filter residue) that come down remain on the filter medium to form a filter cake.
Crystallization: When a hot saturated solution is cooled, the solubility of the solute decreases and the solution becomes supersaturated, so that the solute precipitates in the form of crystals.
Separation: Dry and wet separation.
Drying: Use heat to vaporize moisture (moisture or other solvents) in wet materials, and use airflow or vacuum to take away the vaporized moisture to obtain dry materials.
Screening: The material is sorted by particle size.
Packaging: Finished packaging.
Screening purpose
In the synthesis of intermediates, the particle size of the material is different, and the fineness of the powder is not uniform, which is depreciated or even rejected. The material is sticky, adsorbed, screened and blocked, the surface shape of the material, and the bulk density are strictly required, and it cannot be damaged or damaged, such as the raw materials of capsules and pellets.
